Media・Award受賞/記事紹介

Bioprosthetic Valve Deterioration: Accumulation of Circulating Proteins and Macrophages in the Valve Interstitium. JACC Basic Transl Sci.

Sakaue T, Koyama T, Nakamura Y, Okamoto K, Kawashima T, Umeno T, Nakayama Y, Miyamoto S, Shikata F, Hamaguchi M, Aono J, Kurata M, Namiguchi K, Uchita S, Masumoto J, Yamaguchi O, Higashiyama S, Izutani H.

2023 May 10;8(7):862-880. doi:10.1016/j.jacbts.2023.01.003. PMID: 37547071; PMCID: PMC10401294.

Aortic valve neocuspidization with in-body tissue-engineered autologous membranes: preliminary results in a long-term goat model. Interact Cardiovasc Thorac Surg.

Kawashima T, Umeno T, Terazawa T, Wada T, Shuto T, Nishida H, Anai H, Nakayama Y, Miyamoto S.

2021 May 27;32(6):969-977. doi:10.1093/icvts/ivab015. PMID: 33543242; PMCID: PMC8691585.

Mechanical characterization of an in-body tissue-engineered autologous collagenous sheet for application as an aortic valve reconstruction material. J Biomech.

Terazawa T, Kawashima T, Umeno T, Wada T, Ozaki S, Miyamoto S, Nakayama Y.

2020 Jan 23;99:109528. doi: 10.1016/j.jbiomech.2019.109528. Epub 2019 Nov 18. PMID: 31780124.

Implanted In-Body Tissue-Engineered Heart Valve Can Adapt the Histological Structure to the Environment. ASAIO J.

Takewa Y, Sumikura H, Kishimoto S, Naito N, Iizuka K, Akiyama D, Iwai R, Tatsumi E, Nakayama Y.

2018 May/Jun;64(3):395-405. doi:10.1097/MAT.0000000000000769. PMID: 29517511.

Development of a stent-biovalve with round-shaped leaflets: in vitro hydrodynamic evaluation for transcatheter pulmonary valve implantation (TPVI). J Artif Organs.

Sumikura H, Nakayama Y, Ohnuma K, Takewa Y, Tatsumi E.

2016 Dec;19(4):357-363. doi: 10.1007/s10047-016-0909-6. Epub 2016 May 26. PMID: 27230085.

Development of an in vivo tissue-engineered valved conduit (type S biovalve) using a slitted mold. J Artif Organs.

Funayama M, Furukoshi M, Moriwaki T, Nakayama Y.

2015 Dec;18(4):382-6. doi: 10.1007/s10047-015-0856-7. Epub 2015 Aug 2. PMID: 26233653.

In vitro hydrodynamic evaluation of a biovalve with stent (tubular leaflet type) for transcatheter pulmonary valve implantation. J Artif Organs.

Sumikura H, Nakayama Y, Ohnuma K, Kishimoto S, Takewa Y, Tatsumi E.

2015 Dec;18(4):307-14. doi: 10.1007/s10047-015-0851-z. Epub 2015 Jul 4. PMID: 26141924.

Successful implantation of autologous valved conduits with self-expanding stent (stent-biovalve) within the pulmonary artery in beagle dogs. J Vet Cardiol.

Funayama M, Matsui Y, Tajikawa T, Sasagawa T, Saito Y, Sagishima S, Mizuno T, Mizuno M, Harada K, Uchida S, Shinoda A, Iwai R, Nakayama Y, Uechi M.

2015 Mar;17(1):54-61. doi: 10.1016/j.jvc.2014.12.003. Epub 2015 Feb 16. PMID: 25697493.

Development of self-expanding valved stents with autologous tubular leaflet tissues for transcatheter valve implantation. J Artif Organs.

Funayama M, Sumikura H, Takewa Y, Tatsumi E, Nakayama Y.

2015 Sep;18(3):228-35. doi:10.1007/s10047-015-0820-6. Epub 2015 Feb 12. PMID: 25672940.

Sutureless aortic valve replacement using a novel autologous tissue heart valve with stent (stent biovalve): proof of concept. J Artif Organs.

Kishimoto S, Takewa Y, Nakayama Y, Date K, Sumikura H, Moriwaki T, Nishimura M, Tatsumi E.

2015 Jun;18(2):185-90. doi: 10.1007/s10047-015-0817-1. Epub 2015 Jan 21. PMID: 25604149.

In situ observation and enhancement of leaflet tissue formation in bioprosthetic “biovalve”. J Artif Organs. 2015 Mar;18(1):40-7. doi: 10.1007/s10047-014-0793-x. Epub

Funayama M, Takewa Y, Oie T, Matsui Y, Tatsumi E, Nakayama Y.

2014 Nov 5. PMID: 25370717.

In-body tissue-engineered aortic valve (Biovalve type VII) architecture based on 3D printer molding. J Biomed Mater Res B Appl Biomater.

Nakayama Y, Takewa Y, Sumikura H, Yamanami M, Matsui Y, Oie T, Kishimoto Y, Arakawa M, Ohmuma K, Tajikawa T, Kanda K, Tatsumi E.

2015 Jan;103(1):1-11. doi: 10.1002/jbm.b.33186. Epub 2014 Apr 25. PMID: 24764308.

Preparation of an autologous heart valve with a stent (stent-biovalve) using the stent eversion method. J Biomed Mater Res B Appl Biomater.

Mizuno T, Takewa Y, Sumikura H, Ohnuma K, Moriwaki T, Yamanami M, Oie T, Tatsumi E, Uechi M, Nakayama Y.

2014 Jul;102(5):1038-45. doi: 10.1002/jbm.b.33086. Epub 2013 Dec 9. PMID: 24323669.

In vitro evaluation of a novel autologous aortic valve (biovalve) with a pulsatile circulation circuit. Artif Organs.

Sumikura H, Nakayama Y, Ohnuma K, Takewa Y, Tatsumi E.

2014 Apr;38(4):282-9. doi: 10.1111/aor.12173. Epub 2013 Nov 14. PMID: 24237157.

In vivo evaluation of an in-body, tissue-engineered, completely autologous valved conduit (biovalve type VI) as an aortic valve in a goat model. J Artif Organs.

Takewa Y, Yamanami M, Kishimoto Y, Arakawa M, Kanda K, Matsui Y, Oie T, Ishibashi-Ueda H, Tajikawa T, Ohba K, Yaku H, Taenaka Y, Tatsumi E, Nakayama Y.

2013 Jun;16(2):176-84. doi: 10.1007/s10047-012-0679-8. Epub 2012 Dec 20. PMID: 23254363.

Water-soluble argatroban for antithrombogenic surface coating of tissue-engineered cardiovascular tissues. J Biomed Mater Res B Appl Biomater.

Nakayama Y, Yamaoka S, Yamanami M, Fujiwara M, Uechi M, Takamizawa K, Ishibashi-Ueda H, Nakamichi M, Uchida K, Watanabe T, Kanda K, Yaku H.

2011 Nov;99(2):420-30. doi: 10.1002/jbm.b.31914. Epub 2011 Sep 27. PMID: 21953850.

A completely autologous valved conduit prepared in the open form of trileaflets (type VI biovalve): mold design and valve function in vitro. J Biomed Mater Res B Appl Biomater.

Nakayama Y, Yahata Y, Yamanami M, Tajikawa T, Ohba K, Kanda K, Yaku H.

2011 Oct;99(1):135-41. doi: 10.1002/jbm.b.31880. Epub 2011 Jun 28. PMID: 21714078.

Development of a completely autologous valved conduit with the sinus of Valsalva using in-body tissue architecture technology: a pilot study in pulmonary valve replacement in a beagle model. Circulation.

Yamanami M, Yahata Y, Uechi M, Fujiwara M, Ishibashi-Ueda H, Kanda K, Watanabe T, Tajikawa T, Ohba K, Yaku H, Nakayama Y.

2010 Sep 14;122(11 Suppl):S100-6. doi:10.1161/CIRCULATIONAHA.109.922211. PMID: 20837900.

Preparation of in-vivo tissue-engineered valved conduit with the sinus of Valsalva (type IV biovalve). J Artif Organs.

Yamanami M, Yahata Y, Tajikawa T, Ohba K, Watanabe T, Kanda K, Yaku H, Nakayama Y.

2010 Jul;13(2):106-12. doi: 10.1007/s10047-010-0491-2. Epub 2010 Mar 6. PMID: 20213453.

Preparation of a completely autologous trileaflet valve-shaped construct by in-body tissue architecture technology. J Biomed Mater Res B Appl Biomater.

Nakayama Y, Yamanami M, Yahata Y, Tajikawa T, Ohba K, Watanabe T, Kanda K, Yaku H.

2009 Nov;91(2):813-818. doi: 10.1002/jbm.b.31460. PMID: 19582849.